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. 2018 Jan 31;38(5):1249–1263. doi: 10.1523/JNEUROSCI.2988-17.2017

Figure 4.

Figure 4.

GnRH neuron excitability is independent of time of day and estradiol feedback in kisspeptin KO mice. A, Mean ± SEM number of spikes elicited during 500 ms current injection (0–30 pA, 2 pA steps). B–H, Individual values and mean ± SEM. B, Latency to first spike. C, Action potential threshold. D, Action potential amplitude. E, FWHM. F, Action potential rate of rise. G, AHP amplitude. H, AHP time. *p < 0.05, two-way repeated-measures ANOVA/Bonferroni test (A; group: F(2,22) = 0.9; current: F(15,330) = 128.4, p < 0.001; group × current: F(30,330) = 0.6), one-way ANOVA/Bonferroni (B; F(2,22) = 0.06; C; F(2,22) = 0.7; D; F(2,22) = 3.2, p = 0.06; E; F(2,22) = 4.0, p < 0.05; G; F(2,22) = 1.15; H; F(2,22) = 2.93, p = 0.07) or Kruskal–Wallis/Dunn's (F; F(2,22) = 2.93, p = 0.07).