Table 2.

Results of Tajima’s D and Fu’s F_s neutrality tests applied to global and regional populations of Plasmodium falciparum and P. vivax. Statistically significant P values are underlined.

Population	P. falciparum				P. vivax
	Tajima’s D	P value	Fu’s Fs	P value	Tajima’s D	P value	Fu’s Fs	P value
AFRa	−2.78152	<0.0001	−14.28997	<0.02	−2.73599	<0.0001	−6.32855	<0.02
CAMb	1.29320	0.889	−1.31251	<0.10	−2.14553	<0.0001	−4.08699	<0.02
EASc	—	—	—	—	−0.98766	0.15	−1.74506	>0.10
MCAd	—	—	—	—	−1.90704	0.01	−3.05478	<0.05
MELe	−2.10716	0.003	−4.63388	<0.02	−2.32606	<0.0001	−4.11114	<0.02
SAMf	−2.61638	<0.0001	−8.87358	<0.02	−2.53550	<0.0001	0.03668	>0.10
SEAg	−2.21823	<0.0001	−6.27935	<0.02	−2.16371	<0.0001	−6.61222	<0.02
SOAh	−1.89148	0.008	−2.88087	<0.05	−2.55500	<0.0001	−5.32889	<0.02
Total	−2.68819	<0.0001	−18.2203	<0.02	−2.61983	0.001	−7.09593	<0.02

^aAFR = Africa; ^bCAM = Central America (including Mexico in the P. vivax analyses); ^cEAS = East Asia (only P. vivax); ^dMCA = Middle East and Central Asia (only P. vivax); ^eMEL = Melanesia; ^fSAM = South America; ^gSEA = Southeast Asia; and ^hSOA = South Asia.