Table 1.
Stage of Assessment | E15.5 | E18.5 | P30 | ||||
---|---|---|---|---|---|---|---|
Location | Cochlea | Vestibular System | Cochlea | Vestibular System | Inner Ear | ||
Epithelium | Subepithelium | Epithelium | Subepithelium | ||||
WT | 2.33 ± 1.33 (n = 5) | 3.33 ± 1.45 (n = 5) | 0.67 ± 0.67 (n = 5) | 1.67 ± 0.88 (n = 5) | 2.00 ± 2.10 (n = 10) *CX30 ( + ) Cell; at Spiral Limbus (n = 1/3) | 0.90 ± 1.22 (n = 10) | 0 (n = 5) |
CX30−/− | NP | NP | NP | NP | 5.60 ± 1.62 (n = 5) *CX30 ( + ) Cells; at Spiral Limbus or Reissner’s Membrane (n = 2/2) | 1.00 ± 1.10 (n = 5) | NP |
Data indicate the mean ± SE of the engrafted cells with STEM101 positive. The asterisks indicate the locations where CX30 (+) cells were detectable, and the numbers in the parentheses indicate the numbers of animals which had CX30-positive cells/the number of animals on which we performed immunostaining with CX30. “n” indicates the number of animals on which we performed immunostaining with STEM101. “NP” stands for not performed.