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. 2018 Jan 7;12(2):239–255. doi: 10.1002/1878-0261.12161

Table 1.

Candidate genes identified in this study. Genes identified to be associated with metastasis and poor patient prognosis. This table shows gene expression on a continuous scale. The hazard ratios (HR) shown are per each additional unit of log2 gene expression

Gene Leeds cohort Melanoma‐Specific Survival Lund cohort overall survival
Hazard Ratio 95% C.I. P‐val FDR Hazard Ratio 95% C.I. P‐val FDR
CD82 0.58415 0.48411, 0.70485 2.03E‐08 0.00020 0.52520 0.37432, 0.73692 0.00019 0.00153
LFNG 0.60248 0.45858, 0.79153 0.00027 0.01102 0.52328 0.38240, 0.71605 5.18E‐05 0.00055
PTK2B 0.64250 0.52325, 0.78893 2.41E‐05 0.00364 0.47279 0.31916, 0.70039 0.00019 0.00148
CCL5 0.67761 0.56575, 0.81157 2.35E‐05 0.00360 0.57686 0.41392, 0.80393 0.00116 0.00629
LSP1 0.68714 0.57354, 0.82325 4.71E‐05 0.00497 0.48760 0.33130, 0.71764 0.00027 0.00201
DDX60 0.71537 0.59150, 0.86520 0.00056 0.01594 0.53727 0.34560, 0.83524 0.00578 0.02156
PARP14 0.71561 0.58722, 0.87208 0.00091 0.02035 0.57359 0.37679, 0.87319 0.00953 0.03145
TUBA4A 0.71722 0.60117, 0.85567 0.00022 0.01002 0.31663 0.23623, 0.42440 1.42E‐14 4.79E‐12
GPX3 0.71882 0.60071, 0.86016 0.00031 0.01170 0.26009 0.10878, 0.62186 0.00246 0.01130
NDUFA4L2 0.72297 0.60147, 0.86901 0.00055 0.01588 0.67309 0.50482, 0.89746 0.00700 0.02488
GABRE 0.72349 0.59532, 0.87925 0.00114 0.02295 0.42004 0.28150, 0.62674 2.16E‐05 0.00028
BTBD6 0.72365 0.58391, 0.89682 0.00313 0.04005 0.47218 0.25171, 0.88574 0.01938 0.05445
ITM2A 0.72406 0.60252, 0.87011 0.00057 0.01613 0.35698 0.25098, 0.50776 1.00E‐08 3.96E‐07
HDC 0.73176 0.61012, 0.87764 0.00076 0.01881 0.63449 0.51806, 0.77708 1.09E‐05 0.00016
ELF4 0.73257 0.61273, 0.87584 0.00064 0.01716 0.56910 0.38619, 0.83865 0.00438 0.01738
RIPK3 0.73743 0.62606, 0.86861 0.00027 0.01085 0.40256 0.30353, 0.53388 2.67E‐10 1.57E‐08
CCBE1 0.73817 0.59969, 0.90862 0.00418 0.04704 0.35930 0.14251, 0.90584 0.03004 0.07619
PON3 0.74237 0.61458, 0.89673 0.00200 0.03083 0.64187 0.53994, 0.76304 5.02E‐07 1.23E‐05
BOC 0.74269 0.61053, 0.90345 0.00292 0.03872 0.67546 0.50016, 0.91219 0.01048 0.03398
RUNX1T1 0.74951 0.61916, 0.90730 0.00310 0.03987 0.57779 0.40754, 0.81917 0.00207 0.00983
FILIP1L 0.76881 0.64177, 0.92100 0.00433 0.04808 0.49836 0.36807, 0.67478 6.67E‐06 0.00011
NDRG2 0.77243 0.64328, 0.92751 0.00567 0.05603 0.56030 0.40811, 0.76923 0.00034 0.00241
TSPAN33 0.77331 0.65148, 0.91792 0.00329 0.04124 0.46715 0.24663, 0.88486 0.01953 0.05474
FAM110C 0.77589 0.64552, 0.93259 0.00686 0.06188 0.62169 0.44282, 0.87281 0.00603 0.02221
JUP 0.77882 0.65184, 0.93053 0.00591 0.05722 0.61515 0.51528, 0.73437 7.62E‐08 2.36E‐06
RUNX3 0.78039 0.64937, 0.93784 0.00818 0.06857 0.34593 0.21468, 0.55742 1.29E‐05 0.00018
EGLN3 0.78592 0.64904, 0.95166 0.01361 0.09212 0.42935 0.31385, 0.58735 1.23E‐07 3.61E‐06
MID1 1.37339 1.09496, 1.72262 0.00606 0.05803 3.45380 2.09940, 5.68197 1.06E‐06 2.28E‐05