Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Dec 22;15(3):2333–2342. doi: 10.3892/etm.2017.5673

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Deng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 2. — Sirt7 exhibited oncogenic properties by promoting CRC cell proliferation. (A) Endogenous Sirt7 level was measured in SW620 and HCT116 cells following transduction with corresponding Sirt7 siRNAs or SCR (negative control). GAPDH served as an internal control for each group. (B) MTT assay was performed in SW620 and HCT116 cells transfected with si-Sirt7 or SCR. The OD value was measured every 24 h, demonstrating that knockdown of Sirt7 significantly reduced CRC proliferation. (C) Colony formation number was counted and analyzed in SW620 and HCT116 cells transfected with si-Sirt7 or SCR. *P<0.05 and **P<0.01 vs. corresponding control group. Sirt7, sirtuin 7; CRC, colorectal carcinoma; SCR, scramble control RNA; OD, optical density; si, siRNA.