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. 2017 Dec 22;15(3):2655–2660. doi: 10.3892/etm.2017.5675

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Figure 2. — miR-15 affects the chemosensitivity of colon cancer cells to 5-Fu and OX. (A) 5-Fu induced the expression of miR-15 as determined by RT-qPCR. (B) Overexpression of miR-15 increased the chemosensitivity of colon cancer cells to 5-Fu, as determined by the cell viability assay. (C) OX induced the expression of miR-15, as determined by RT-qPCR. (D) Overexpression of miR-15 increased the chemosensitivity of colon cancer cells to OX as determined by the cell viability assay. Values are presented as the mean ± standard deviation. miR-15, microRNA-15;5-FU, 5-fluorouracil; OX, oxaliplatin; RT-qPCR, quantitative reverse transcription polymerase chain reaction; Ctrol, control.