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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Anaerobe. 2017 Oct 12;48:249–256. doi: 10.1016/j.anaerobe.2017.10.006

Fig. 5. Synergistic effects of TcdA and TcdB.

Fig. 5

Mice were injected with individual toxins (TcdA or TcdB) or their mixtures. The clinical scores at 24 h (A) and survival curves for 72 h (B) are exhibited. Mice with a score (Table 2) equal to or higher than 11 were considered moribund and were euthanized (n = 10 per group) A1: TcdA 1 µg; B5: TcdB 5 µg; A1B5: 1 µg TcdA + 5 µg TcdB; A2B2: 2 µg TcdA + 2 µg TcdB. *: p < 0.05, vs A1B5.