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. 2018 Jan 31;5(1):171113. doi: 10.1098/rsos.171113

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© 2018 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 8. — Schematic representation of the multi-step approach used. (i) Characterization of the particles in suspension to match in vitro tests, (ii) testing of the nanoparticles to quantify their antibacterial response (acute and in a life-cycle scenario), (iii) in vitro test to assess toxic response upon contact (skin model), (iv) testing of collected, purified nanoparticle to assess particle-specific activity, and (v) correlation of relevant properties and nanoparticles activity (antiseptic/toxic and particle-specific).