FIG 6 .

Effect of treatment with IL-12/ms during primary infection with N. gonorrhoeae FA1090 against reinfection with N. gonorrhoeae MS11 persists for 2 months (A), 4 months (B), or 6 months (C) after the clearance of primary infection. The left panels show recovery (mean CFU plus SEM; n = 8) of N. gonorrhoeae on vaginal swabs after reinfection with MS11 at each interval. Curves for mice treated with IL-12/ms are significantly different (P < 0.01 by ANOVA) from the curves for mice treated with blank ms at each interval (indicated by the asterisk). The right panels show percentage of animals remaining infected at each time point (P < 0.001 by Kaplan-Meier analysis), comparing IL-12/ms with blank ms treatment at each interval.