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. 2018 Jan 31;3(1):e00553-17. doi: 10.1128/mSphere.00553-17

TABLE 3 .

Phenotypic characteristics of the ancestral Escherich strain isolates

Isolate Mutation ratea Mouse model of
extraintestinal
virulenceb 		Antimicrobial
susceptibility
profilec
NCTC86 4.38 ⋅ 10−7 0/10 Sd
CIP61.11 1.28 ⋅ 10−6 0/10 Se
ATCC 4157 8.29 ⋅ 10−7 0/10 Sf
DSM301 2.11 ⋅ 10−7 0/10 Sd
a

Mutation rates correspond to median values of five independent experiments, with E. coli CIP2.83 and M13 being used as nonmutator (mutation rate, 7.80 ⋅ 10−9) and MMR-deficient (mutation rate, 1.32 ⋅ 10−7) control strains, respectively.

b

The number of mice killed by the isolate/number of mice inoculated is shown. CFT073 was used as the killer control strain (10/10), and K-12 MG1655 was the nonkiller control strain (0/10).

c

S, susceptibility to all of the antibiotics tested except erythromycin.

d

Hypersusceptible to ampicillin, piperacillin, ticarcillin-clavulanic acid, cephalothin, cefixime, cefotaxime, aztreonam, chloramphenicol, tetracycline, nalidixic acid, levofloxacin, ofloxacin, ciprofloxacin, norfloxacin, moxifloxacin, gentamicin, and co-trimoxazole.

e

Hypersusceptible to amoxicillin, ampicillin, piperacillin, ticarcillin-clavulanic acid, cephalothin, cefixime, cefotaxime, aztreonam, chloramphenicol, tetracycline, colistin, nalidixic acid, levofloxacin, ofloxacin, ciprofloxacin, norfloxacin, moxifloxacin, streptomycin, gentamicin, and co-trimoxazole.

f

Hypersusceptible to ampicillin, piperacillin, ticarcillin-clavulanic acid, cefixime, cefotaxime, aztreonam, chloramphenicol, tetracycline, nalidixic acid, levofloxacin, ofloxacin, ciprofloxacin, norfloxacin, moxifloxacin, streptomycin, gentamicin, and co-trimoxazole.