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. 2018 Jan 4;9(1):16. doi: 10.3390/genes9010016

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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SNCA is modulated by the EGFR signaling pathway. (A) FunRichsoftware identified the EGFR1 signaling pathway as one of the top significant GO biological processes associated with SNCA; (B) The PPI network of SNCA interaction partners, created using the FunRich algorithm; (C) The GEPIA tool showed a negative correlation between SNCA and EGFR transcript levels in ADC tissues; (D) Putative EGFR phosphorylation sites were predicted in the SNCA protein sequence using the PhosphoNET website (http://www.phosphonet.ca/).