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. 2018 Jan 22;9(1):56. doi: 10.3390/genes9010056

Table 1.

The top 5 up- and down- regulated genes with confirmed biological function.

Gene symbol Log(FCA) Biological Function
EIF1AY 3.44 Chromatin organization
UTY 2.28 Chromatin organization
USP9Y 2.12 Ubiquitin-Proteasome Dependent Proteolysis
RPS4Y1 1.95 Chromatin organization
DDX3Y 1.78 Translational initiation
SERPINA3 −3.04 Immune Response to elevated platelet cytosolic Ca2+
MYOT −2.27 Structural constituent of muscle
S100A8 −2.03 Immune System (Activated TLR4 signaling)
FCN3 −1.96 Immune System (Lectin pathway of complement activation)
CD163 −1.86 Scavenger Receptors signaling

FCA: average fold change of gene expression values; TLR4:Toll-like receptor 4.