Table 1.
Correlations between gut hormones, energy intake, and gastric emptying.
Energy Intake | Gastric Emptying (T50) | |||
---|---|---|---|---|
r | p | r | p | |
Glucose | 0.05 | 0.68 | −0.14 | 0.28 |
Insulin | −0.41 | 0.001 | 0.80 | <0.001 |
Glucagon | −0.34 | 0.005 | 0.81 | <0.001 |
Ghrelin | 0.36 | 0.003 | −0.53 | <0.001 |
CCK | −0.33 | 0.008 | 0.77 | <0.001 |
GIP | −0.32 | 0.008 | 0.75 | <0.001 |
GLP-1 | −0.31 | 0.011 | 0.68 | <0.001 |
r and p values of within-subject correlations between energy intake (0 g (control, ~2 kcal), 30 g (120 kcal) and 70 g (280 kcal) whey protein intake: younger n = 16: 1082 ± 106 kcal, 963 ± 79 kcal, 948 ± 82 kcal; older n = 16: 843 ± 77 kcal, 803 ± 75 kcal, 793 ± 78 kcal), gastric empting half time (T50; control, 30 and 70 g whey protein intake: younger n = 16: 16 ± 1 min, 32 ± 3 min, 85 ± 10 min; older n = 15: 23 ± 2 min, 65 ± 7 min, 130 ± 10 min) and blood glucose (mmol/L), plasma insulin (mU/L), glucagon (pg/mL), ghrelin (pg/mL), CCK (pmol/L), GIP (pmol/L), and GLP-1 (pmol/L) concentrations (AUC 0–180 min) in healthy older and younger adults. Within-subject correlations were determined by using a general linear model with fixed slope and random intercept.