Table 2.
Group | Organ Mass (g) | |||||
---|---|---|---|---|---|---|
db/+ | db/db | |||||
Parameters | GEE 0 * | GEE 0 * | GEE 0 * | GEE 50 * | GEE 200 * | |
Metformin 0 * | Metformin 0 * | Metformin 140 * | Metformin 0 * | Metformin 0 * | ||
Subcutaneous fat | 0.30 ± 0.04 d | 1.63 ± 0.13 b | 1.83 ± 0.21 a | 1.53 ± 0.16 bc | 1.45 ± 0.13 c | |
Liver | 1.08 ± 0.07 d | 2.13 ± 0.18 a | 1.89 ± 0.15 bc | 2.05 ± 0.15 ab | 1.84 ± 0.19 c | |
Heart | 0.16 ± 0.03 | 0.15 ± 0.03 | 0.16 ± 0.01 | 0.15 ± 0.02 | 0.15 ± 0.02 | |
Lung | 0.18 ± 0.03 | 0.19 ± 0.04 | 0.19 ± 0.03 | 0.19 ± 0.03 | 0.19 ± 0.03 |
* (mg/kg/day), (n = 8 per group, a p < 0.05, b p < 0.01, c p < 0.001).