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. 2018 Jan 11;10(1):72. doi: 10.3390/nu10010072

Table 4.

Comparison of changes in serum total cholesterol induced by chitosan and placebo treatments.

Placebo Chitosan p-Value Chitosan vs. Placebo
All subjects (mg/dL) −5.13 ± 24.79 −12.51 ± 28.22 *** 0.3336 #
% subjects decrease 63.0 67.2 0.6968 #
% subjects increase 37.0 32.8
Change vs. baseline
Spearman R −0.4792 −0.3587
Spearman p-value 0.0002 0.0045 0.9399
Difference in slope (p-value) 0.0002 $ 0.0066 $ 0.0553 &

Wilcoxon p-value expressing the significance of the change compared to zero, *** p < 0.001, # data are expressed as p-values using the Mann–Whitney test, $ value expresses whether slope is different from zero, & value expresses whether slopes under chitosan and placebo treatments are different.