Table 5.
Comparison of changes in serum low density lipoprotein (LDL) cholesterol induced by chitosan and placebo treatments.
| Placebo ∆ | Chitosan ∆ | p-Value Chitosan vs. Placebo | |
|---|---|---|---|
| All subjects (mg/dL) | −1.00 ± 24.22 | −8.67 ± 18.18 *** | 0.0252 # |
| % subjects decrease | 48.2 | 73.8 | 0.0076 # |
| % subjects increase | 51.8 | 26.2 | |
| Change vs. baseline | |||
| Spearman R | 0.03768 | −0.3995 | |
| Spearman p-value | 0.7868 | 0.0014 | |
| Difference in slope (p-value) | 0.7797 $ | 0.0024 $ | 0.0019 & |
∆ Wilcoxon p-value expressing the significance of the change compared to zero, *** p < 0.001, # data are expressed as p-values using the Mann–Whitney test, $ value expresses whether slope is different from zero, & value expresses whether slopes under chitosan and placebo treatments are different.