Skip to main content
. 2018 Jan 15;10(1):91. doi: 10.3390/nu10010091

Figure 7.

Figure 7

Effect of deoxyschizandrin on the mRNA expression and production of MMP-9, RANTES, and VEGF in tumour-associated macrophages (TAMs); THP-1 cells were stimulated with conditioned medium from A2780 cells and were treated with the indicated concentration of deoxyschizandrin (15 and 30 µM) for 48 h. (A) Real-time RT-PCR was conducted to measure the mRNA levels of MMP-9, RANTES, and VEGF in macrophages; (B) Western blot analysis was performed to measure the production levels of MMP-9 in cell culture media. Band images are representatives of three individual experiments and the results of densitometry represent the mean ± SD of three independent experiments. Production levels of RANTES and VEGF in cell culture media were measured using ELISA assay. The values represent the mean ± SD of results from three independent experiments. # p < 0.05 vs. MQ; * p < 0.05 vs. the untreated TAMs.