Table 2.
Advantages, disadvantages, and exercise performance in continuous and flash glucose monitoring systems.
| Advantage | Disadvantage | Exercise Performance | |
|---|---|---|---|
| Dexcom G5TM | Hypo- and hyperglycemia alerts; rise and fall (rate of change) alerts; compatible with mobile devices; online live monitoring with different mobile devices (e.g., for parents), CE 1 mark (European Union). Approved for non-adjuvant use; compatible with Apple iPhone 4S and subsequent iOS models |
Requires calibration to blood glucose; no integrated bolus wizard | N/A for Dexcom G5TM |
| Dexcom G4TM | Hypo- and hyperglycemia alerts; rise and fall (rate of change) alerts; available integrated with the Animas Vibe pump | Requires calibration to blood glucose; no integrated bolus wizard | Continuous exercise: MARD 2 13.6–18.6%; interval exercise: MARD 13.3–17.7% [61,64,76] (interstitial glucose compared to venous plasma glucose) |
| Medtronic 670 G with SmartGuard® | Hybrid closed-loop system when combined with insulin pump (automatic insulin delivery when glucose is high); predictive low glucose-suspend when combined with insulin pump; predictive low glucose alert; hypo- and hyperglycemia alerts; rise and fall (rate of change) alerts; Bluetooth connected to glucometer (CONTOUR, NEXT LINK 2.4); bolus wizard | Requires calibration to blood glucose | N/A 3 for this specific system |
| Medtronic 640 G with SmartGuard® | Predictive low glucose-suspend when combined with insulin pump; predictive low glucose alert; hypo- and hyperglycemia alerts; rise and fall (rate of change) alerts; Bluetooth connected to glucometer (CONTOUR, NEXT LINK 2.4); bolus wizard | Requires calibration to blood glucose | Continuous exercise: MARD 19.4% [61] (interstitial glucose compared to venous plasma glucose) |
| Medtronic Paradigm Minimed® Veo (530 G) | Low-glucose-suspend when combined with insulin pump; hypo- and hyperglycemia alerts; rise and fall (rate of change) alerts; Bluetooth connected to glucometer (CONTOUR, NEXT LINK 2.4); bolus wizard; | Requires calibration to blood glucose | Continuous exercise: MARD 12.8–23.7%; interval exercise: MARD 15.5–26.5% [63] (interstitial glucose compared to capillary blood glucose) |
| FreeStyle® Libre Flash glucose monitoring | Factory-calibrated; long sensor lifetime (14 days); integrated glucometer; integrated blood ketone measurement; cheap sensor costs; integrated bolus wizard | No automatic hypo- or hyperglycemia alerts; not combinable with pump | Continuous exercise: MARD 8.7% [61] (interstitial glucose compared to venous plasma glucose) |
| FreeStyle® Navigator II CGM system | 30 m transmission range; new result every minute; hypo- and hyperglycemia alerts; early warning alarms; integrated glucometer | Fixed time points for calibration: 1, 2, 10, 24, and 72 h after sensor insertion | N/A for the second generation |
1 CE (Conformité Européenne) marking is a certification mark that indicates conformity with health, safety, and environmental protection standards for products sold within the European Economic Area. 2 MARD: Median Absolute Relative Difference. 3 N/A: Not Applicable.