Table 5.
Association of post-bronchodilator ratio FEV1/FVC and FEV1/FVC < LLN with dietary intake of flavonoids.
| Flavonoid Subclass (Quintiles; mg) | FEV1/FVC (Continuous) | FEV1/FVC < LLN (Binary) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Effect Size (Regression Coefficient and 95% Confidence Interval) Per-Quintile Increase in Flavonoid Intake | OR (95% Confidence Interval) Highest vs. Lowest Quintile of Flavonoid Intake | |||||||||||||
| Model 1 (n = 2599) | p-Value | Model 2 (n = 2599) | p-Value | p-Value after Simes’ Procedure | Model 1 (n = 2599) | p-Value | Model 2 (n = 2599) | p-Value | p-Value after Simes’ Procedure | |||||
| Total flavanoids | 0.50 | (0.29 to 0.72) | <0.0001 | 0.33 | (0.10 to 0.57) | 0.01 | 0.02 | 0.58 | (0.39 to 0.86) | 0.01 | 0.61 | (0.39 to 0.97) | 0.04 | 0.12 |
| Flavanones | 0.16 | (−0.05 to 0.37) | 0.15 | 0.07 | (−0.30 to 0.17) | 0.57 | 0.71 | (0.47 to 1.08) | 0.11 | 0.84 | (0.51 to 1.37) | 0.49 | ||
| Anthocyanins | 0.34 | (0.13 to 0.56) | 0.002 | 0.12 | (−0.15 to 0.39) | 0.39 | 0.58 | (0.39 to 0.86) | 0.01 | 0.73 | (0.43 to 1.24) | 0.25 | ||
| Flavan-3-ols | 0.42 | (0.21 to 0.63) | 0.0001 | 0.20 | (−0.02 to 0.42) | 0.07 | 0.65 | (0.44 to 0.97) | 0.03 | 0.73 | (0.47 to 1.11) | 0.14 | ||
| Flavonols | 0.34 | (0.13 to 0.56) | 0.002 | 0.18 | (−0.06 to 0.42) | 0.14 | 0.77 | (0.52 to 1.14) | 0.19 | 0.92 | (0.58 to 1.47) | 0.74 | ||
| Flavones | 0.31 | (0.1 to 0.52) | 0.004 | 0.17 | (−0.07 to 0.4) | 0.16 | 0.80 | (0.54 to 1.18) | 0.26 | 1.01 | (0.63 to 1.6) | 0.97 | ||
| Polymers | 0.48 | (0.27 to 0.69) | <0.0001 | 0.32 | (0.09 to 0.55) | 0.01 | 0.02 | 0.55 | (0.37 to 0.81) | 0.002 | 0.56 | (0.36 to 0.88) | 0.01 | 0.09 |
| Pro-anthocyanidins | 0.58 | (0.37 to 0.79) | <0.0001 | 0.44 | (0.19 to 0.69) | 0.001 | 0.004 | 0.58 | (0.39 to 0.85) | 0.01 | 0.61 | (0.37 to 0.99) | 0.04 | 0.12 |