Table 1.
Therapy | Target | Cancer type | Reference | |
---|---|---|---|---|
Specific | R428 | Axl | Breast cancer, GBM, AML and Ewing sarcoma | [74, 76–78] |
UNC1062 | Mer | melanoma | [39] | |
UNC2025 | Mer | GBM | [87] | |
Mer590 | Mer | NSCLC | [88] | |
Non-specific | shRNA | Axl | Breast carcinoma | [65] |
shRNA | Mer | Melanoma and AML | [39, 42] | |
siRNA | Tyro3 | Breast cancer | [23] |
Gas6 growth arrest-specific gene 6, AML acute myeloid leukaemia, GBM glioblastoma multiforme, NSCLC non-small-cell lung cancer