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. 2018 Jan 31;17:20. doi: 10.1186/s12943-018-0769-1

Table 1.

Research on targeting Gas6/TAM for cancer therapy

Therapy Target Cancer type Reference
Specific R428 Axl Breast cancer, GBM, AML and Ewing sarcoma [74, 7678]
UNC1062 Mer melanoma [39]
UNC2025 Mer GBM [87]
Mer590 Mer NSCLC [88]
Non-specific shRNA Axl Breast carcinoma [65]
shRNA Mer Melanoma and AML [39, 42]
siRNA Tyro3 Breast cancer [23]

Gas6 growth arrest-specific gene 6, AML acute myeloid leukaemia, GBM glioblastoma multiforme, NSCLC non-small-cell lung cancer