Fig. 7.

Cir-ITCH suppressed tumor formation of xenograft in nude mice. a Representative image of the nude mice injected with T24 cells. b Representation picture of tumor formation of xenograft in nude mice (n = 5). c Summery of tumor volume of mice which were measured every week(*P < 0.05, **P < 0.01, Student’s t-test). d Weights of tumors in two groups were measured using electronic scales (*P < 0.05, Student’s t-test). e Proteins was extracted from the tumors and the protein expression of p21/PTEN was measured using western blot. f The expression of p21/PTEN was also measured using IHC in xenograft (Magnification, × 200)