Table 2.

Sensitivity and specificity, PPV and NPV of a panel of coagulation tests for detecting > = 30 ng/mL dabigatran or rivaroxaban and correlation with the calibrated activity measurement of dabigatran or rivaroxaban

	Dabigatran					Rivaroxaban
Detection ≥30 ng/mL	Sensitivity	Specificity	PPV	NPV	R2	Sensitivity	Specificity	PPV	NPV	R2
APTT Actin FSL	93	67	92	78	0.59	67	81	95	30	0.53
APTT Cephascreen	100	28	85	100	0.71	85	62	93	42	0.55
PT neoplastin	93	39	86	58	0.19	98	24	88	63	0.81
PT Innovin	49	78	90	27	0.09	68	67	92	27	0.26
TT Thrombin clotin	100	33	86	100	0.18	–	–	–	–	–
TT Thrombin	100	39	86	100	0.72	–	–	–	–	–
CT-INTEM ROTEM®	52	50	86	15	0.63	77	80	95	36	0.69
CT-EXTEM ROTEM®	91	75	86	15	0.51	96	75	96	75	0.58

PPV Positive predictive value, NPV Negative predictive value, APTT Activated partial thrombin time, PT Prothrombin time, TT Thrombin time, CT Closure time