Table 1.
Bacterial numbers in dentinal lesions (at baseline and after biofilm challenge) and bacterial reduction compared with baseline (before treatment).
Treatment | Bacterial Counts (CFU/μg) | Reduction | |
---|---|---|---|
(Baseline) | (After Biofilm-Challenge) | ||
Con | 1721 (977/2671) | 1451 (827/2645) a | −17% (−57/120%) a |
NaF | 1231 (458/5185) | 750 (260/1401) ab | −8% (−96/178%) a |
CHX | 929 (417/3530) | 190 (73/517) c | −87% (−98/−68%) b |
SDF | 1680 (625/4058) | 360 (136/1166) bc | −75% (−95/8%) a |
Samples were submitted to no treatment (Con), daily sodium fluoride (NaF) rinses only, chlorhexidine (CHX) or silver diamine fluoride (SDF) varnishes plus daily NaF rinses. Colony forming units per μg dentin (CFU/μg) and reductions (in percent compared with baseline) are reported as median (25th/75th percentiles). Different superscript letters indicate statistically significant differences between groups (p < 0.05, Mann–Whitney/Bonferroni) (for example, for reduction in CFU counts, CHX (subscript letter b) is significantly different than all other groups (subscript letter a)). n = 25/group.