Supplementary Material 4.

Logistic regression (model: binary logit; optimization: Fischer’s scoring) with stepwise elimination to indicate only significant variables and two-way-interactions regarding the composite outcome need for catecholamines AND need for invasive ventilation AND fatal outcome for patients with enterococcal or nonenterococcal bacteremia. Reciprocal dependence of the three parameters of the composite outcome had been proven by crosstabs (data not shown). Significance was assessed by chi-square testing

Odds ratio estimates and Wald confidence intervalsa
	Enterococcal bacteremia			Nonenterococcal bacteremia
Effect	Estimate	95% Confidence limits	P	Estimate	95% Confidence Limits	P
Intensive care unit vs. no-intensive care unit	13.05	5.23-36.20	<0.01	18.15	10.81-31.41	<0.01
Antibiotic therapy at time point of sample acquisition vs. no such therapy at this time point	3.08	1.27-7.71	<0.01	2.80	1.65-4.85	<0.01
Temperature >38.5°C with vs. without stomata	6.75	2.02-22.58	<0.01	-	-	-
Stomata vs. no stomata	-	-	-	3.04	1.46-6.49	<0.01
Catheter vs. no catheter	-	-	-	3.54	1.29-11.73	0.02

^aDetection of bacteria in bronchoalveolar lavage or urine samples as well as the parameters leukocytes in urine and elevated procalcitonin levels were excluded because of incomplete data sets.