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. 2018 Jan 29;6:e4314. doi: 10.7717/peerj.4314

Table 5. Top genes (FDR <0.1) in Yoruba and Cebu found using PrediXcan.

All results are for the TRIG phenotype. Results from both populations and the Global Lipids Genetic Consortium (GLGC) are shown. Six associations discovered in Cebu replicated in the GLGC.

Chr. Tissue Gene name Beta (Yoruba) P (Yoruba) FDR (Yoruba) Beta (Cebu) P (Cebu) FDR (Cebu) Beta (GLGC) P (GLGC)
2p23.3 THYROID FNDC4 0.05 0.50 0.99 −0.24 1.0 × 10−6 0.037 −0.11 7.7 × 10−83
11p13 ARTAORT PAX6 −0.74 4.8 × 10−7 0.093 0.16 0.20 0.98 0 0.91
11q23.3 ESPMCS BACE1 0.22 0.33 0.99 −3.30 1.7 × 10−15 3.0 × 10−10 −0.17 7.3 × 10−19
11q23.3 CLNSGM APOA4 0.80 0.55 0.99 −11.6 6.5 × 10−12 5.9 × 10−7 −1.95 1.7 ×10−39
11q23.3 BRNHPP APOA1 0.015 0.88 0.99 0.50 3.2 × 10−7 0.019 0 0.31
11q23.3 HRTLV SIDT2 0.24 0.21 0.98 0.90 8.1 × 10−7 0.037 0.16 9.3 × 10−29
11q23.3 THYROID SIDT2 0.10 0.61 0.99 −0.55 1.7 × 10−6 0.050 −0.55 1.1 × 10−102
11q23.3 WHLBLD BACE1 0.00 0.99 0.99 −0.79 3.4 × 10−6 0.087 −0.28 4.0 × 10−28