Endoplasmic reticulum stress response (ERSR) in contused wild type (WT) and activating transcription factor-6 (ATF6α) -/- mice. Total ribonucleic acid (RNA) extracted from injury epicenter of WT and ATF6α-/- mice at 6 h and 24 h-post spinal cord injury show differential effects on ERSR genes (A, B). At 24 h post-SCI, there is no difference in Olig2, MBP, and Claudin11 mRNA levels between the two genotypes (C). Data are the mean ± standard deviation (n = 4, ** p < 0.01).