FIG. 2.

(A) Effect of NIM811 treatment on recovery of reflexive bladder function after spinal cord injury (SCI). Animals treated with either NIM811 20 mg/kg or 40 mg/kg took significantly fewer days (mean ± standard error of the mean [SEM]) to recover reflexive bladder control compared with vehicle and the 10 mg/kg treatment group. *p < 0.05, **p < 0.01. (B) Effect of NIM811 treatment on mean (± SEM) paw withdrawal latencies to assess thermal hyperalgesia after SCI. The data are expressed as post-injury levels of hindpaw latency withdrawal as a mean percentage of the baseline average for each animal.