FIG. 5.

Rolipram-loaded poly(lactide-co-glycolide)-graft-polyethylenimine (Rm-PgP) is retained at spinal cord injury lesion site after local injection. (A) 1,1′-dioctadecyl-3,3,3′,3′-tetramethyl indotricarbocyanine Iodide (DiR) loading in PgP solution and water. (B) Visualization of DiR-PgP nanoparticles by live animal imaging system at 2, 4, 6, 24, 72, and 120 h post-injection. Left: untreated control animal. Right: DiR-PgP injected animal. (C) Images of spinal cord isolated at 2, 4, 6, 24, 72, and 120 h post-injection. Color image is available online at www.liebertpub.com/neu