Fig 1. MBME ASL/BOLD pulse sequence design.

The sequence consists of an unbalanced pCASL labeling train, followed by a PLD, and finally an ME EPI readout. The first echo train was acquired after the acquisition of navigator echoes through the center of k-space. The phase was then rewound to the start of k-space, and the next echo train was acquired. This was repeated three times for a total of four echoes. MB imaging was implemented by replacing the single-band excitation pulse with a MB excitation pulse. Finally, blipped-CAIPI was utilized to shift the FOV of aliased slices and reduce g-factor penalties associated with MB imaging. Reprinted from [31] under a CC BY license, original copyright 2017.