Fig 1. Effects of oral administration of Euglena gracilis Z and paramylon on body weight changes in collagen-induced arthritis mouse model.

DBA/1J mice were sensitized with collagen to establish the collagen-induced arthritis mouse model. The body weight was measured once a week from the end of the quarantine period until booster immunization day, and then three times a week after the booster immunization. Each value represents the mean ± standard error (SE) of five mice.