Table 1. Summary of results.
Tool | Change in body length (tool expressed in BWM) [%] | τrelax [s] | Light sensitivity | Repeatabilityof stimulation | off-ATR excitability | Advantages of the most significant opsins screened | |
---|---|---|---|---|---|---|---|
DEPOLARIZERS | |||||||
ChR2(H134R) | -14.9 | 1.1 | - | ++ | |||
ChR2(C128S) | -14.6 | 181.7 | ++ | - | - | ||
ChR2(L132C) | CatCh | -13.5 | 0.7 | o | |||
ChR2(T159C) | -6.4 | 0.3 | |||||
ChR2(C128S;H134R) | -14.6 | 841.3 | ++ | + | ++ | ||
ChR2(H134R;D156C) | -14.3 | 527.8 | ++++ | ++ | |||
ChR2(H134R;T159C) | -14.7 | 0.6 | |||||
ChR2(C128S;L132C;H134R) | -10.7 | 1253.9 | +++ | ||||
ChR2(L132C;H134R;T159C) | -16.3 | 2.3 | +++ | ||||
ChR2(C128S;L132C;H134R;D156A;T159C) | Quint | -12.8 | 45370.1 | +++ | + | very slow closing kinetics high operational light sensitivity good off-ATR excitability | |
HYPERPOLARIZERS | |||||||
ACR1 | +6.1 | 0.57 | +++++ | + | high photocurrents high operational light sensitivity red-shifted action spectrum | ||
ACR2 | +4.8 | 0.14 | +++++ | + | high photocurrents high operational light sensitivity high temporal precision | ||
ACR1(C102A) | +3.4 | 26.04 | +++++ | ||||
ZipACR | PsuACR_973 | +4.5 | 0.15 | + | + | ||
NpHR | +3.5 | 0.16 | - | + | |||
Mac | +3.9 | 0.09 | + | ||||
Arch | +4.2 | 0.24 | + |