Table 2. Association between SES and access to a second-line DMT for RRMS patients.
| Factors | HR [CI95%] | p-value |
|---|---|---|
| Gender | 0.4192 | |
| Males | 1.00 (Reference) | |
| Females | 0.88 [0.64–1.2] | |
| Age at disease onset | 0.1139 | |
| [6–25 years] | 1.00 (Reference) | |
| [26–35 years] | 0.7 [0.5–0.97] | |
| [36–45 years] | 0.71 [0.47–1.05] | |
| >45 years | 0.61 [0.32–1.14] | |
|
County of residence at diagnosis |
0.0005 | |
| Manche | 1.00 (Reference) | |
| Calvados | 0.56 [0.41–0.77] | |
| Orne | 0.52 [0.33–0.82] | |
| Period of diagnosis | 0.0076 | |
| 1982–2000 | 1.00 (Reference) | |
| 2001–2011 | 1.89 [1.18–3.02] | |
| Year of disease's onset | 1.1 [1.06–1.15] | < 0.0001 |
| EDI (a) (quintiles combined) | 0.0011 | |
| Q2-Q5 | 1.00 (Reference) | |
| Q1 | 1.14 [1.06–1.22] |
(a) Multivariate Cox model for studying EDI effect was performed using EDI as time varying covariate that allows taking into consideration the interaction between EDI and time. (tvc function of STATA ® software).
DMT: Disease Modifying Treatment. RRMS: Relapsing Remitting Multiple Sclerosis. HR: Hazard Ratio. CI: Confidence Interval. EDI: European Deprivation Index.