Table 2. Changes in glomerular proteins expression by immunohistochemistry.
Protein | IA* | 95% CI | IH* | 95% CI | Change from control | p value |
---|---|---|---|---|---|---|
TGF-β1 | 0.041 ± 0.03 | 0.008–0.074 | 0.11 ± 0.04 | 0.057–0.164 | 2.7 X | < 0.05 |
CTGF | 0.15 ± 0.03 | 0.116–0.186 | 0.33 ± 0.05 | 0.263–0.401 | 2.2 X | <0.01 |
VEGF-A | 0.037 ± 0.03 | 0.0007–0.074 | 0.14 ± 0.08 | 0.043–0.243 | 3.8 X | <0.05 |
*: Expressed as mean % of highly-positive DAB chromogen ± SD, DAB: 3,3′-diaminobenzidine, IA: Intermittent air (Control), IH: Intermittent hypoxia, CI: confidence interval, TGF-β1: transforming growth factor-β1, CTGF: connective tissue growth factor, VEGF-A: vascular endothelial growth factor-A.