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. 2018 Feb 1;13(2):e0192050. doi: 10.1371/journal.pone.0192050

Table 2. Incidence and hazard ratio of outcome variables associated with pre-diagnostic and post-diagnostic depression in Cox's regression analysis.

Outcome Pre-diagnostic depression Post-diagnostic depression Crude HR (p-value) Adjusted HR(95% CI) p-value
(N = 227) (N = 126)
Event Person-years Incident rate
(per1000 person-years)
Event Person-years Incident rate
(per1000 person-years)
Death 40 1512 26·5 22 947 23·2 0·83 (0·471) 0·68 (0·40–1·14) 0·146
Accidental injury 40 1278 31·3 36 748 48·1 1·60 (0·041) 1·52 (0·97–2·40) 0·069
Aspiration pneumonia 8 1501 5·3 8 925 8·6 1·50 (0·417) 1·13 (0·42–3·06) 0·807
Dementia 22 1430 15·4 28 818 34·2 2·28 (0·004) 2·01 (1·14–3·53) 0·015

Adjusted HR was adjusted for Age, Gender, Hypertension, Diabetes, Hyperlipidemia, Ischemic heart disease.

HR: hazard ratio, CI: confidence interval, N: case number, %: percentage.