Skip to main content
. 2018 Feb 1;13(2):e0192447. doi: 10.1371/journal.pone.0192447

Fig 2. mRNA expression of lipogenic genes in HepG2 cells following CLAs treatment.

Fig 2

HepG2 cells were incubated with bovine serum albumin (BSA) or with 10 μM of LA, cis-9,trans-11 (c9t11) CLA, cis-9,cis-11 (c9c11) CLA or trans-11,trans-13 (t11t13) CLA for 24 h. The mRNA expression of sterol-regulatory element binding protein-1c (SREBP-1c), SREBP-1a, fatty acid synthase (FAS), stearoyl-CoA desaturase 1 (SCD-1), acetyl-CoA carboxylase α (ACCα), and fatty acid elongase 6 (Elolv6) were measured by qPCR and expressed as relative expression. Data are the means ± SEM of 2 independent experiments (n = 6 to 12). Data with no common superscript letter are significantly different (p ≤ 0.05) according to the post-hoc ANOVA statistical analysis.