Table 1. Hepatic fatty acid profile of mice.

Composition	CT-1	DEF-1	CT-3	DEF-3
C16:0	23.87 ± 0.209	23.69 ± 0.245	23.35 ± 0.312	23.51 ± 0.719
C18:0	10.78 ± 0.642	11.07 ± 0.569	7.563 ± 0.809	6.629 ± 0.287
C20:0	0.155 ± 0.011	0.151 ± 0.007	0.375 ± 0.096	0.2998 ± 0.038
C22:0	0.034 ± 0.003	0.024 ± 0.003*	0.139 ± 0.043	0.047 ± 0.009*
C16:1 cis-9	2.352 ± 0.197	2.512 ± 0.241	4.109 ± 0.395	4.457 ± 0.263
C16 :1 trans-9	0.010 ± 0.001	0.009 ± 0.001	0.000 ± 0.000	0.000 ± 0.000
C18:1 cis-9	15.72 ± 1.109	17.96 ± 0.928	22.15 ± 2.145	36.91 ± 0.776*
C18 :1 cis-11	2.231 ± 0.129	2.728 ± 0.129*	3.495 ± 0.432	5.735 ± 0.223*
C18 :1 trans-9	0.033 ± 0.001	0.042 ± 0.002*	0.081 ± 0.003	0.108 ± 0.012
C18 :1 trans-10	0.004 ± 0.000	0.004 ± 0.000	0.000 ± 0.000	0.000 ± 0.000
C18 :1 trans-11	0.044 ± 0.005	0.049 ± 0.002	0.091 ± 0.020	0.043 ± 0.008*
C18:2 n-6	21.55 ± 0.599	21.52 ± 0.567	22.17 ± 0.241	10.96 ± 0.293*
C20 :4 n-6	12.81 ± 0.662	16.20 ± 0.743*	8.708 ± 1.226	9.494 ± 0.329
C18:3 n-3	0.741 ± 0.068	0.145 ± 0.008*	0.944 ± 0.054	0.217 ± 0.009*
C20 :5 n-3	0.0321 ± 0.012	0.030 ± 0.002*	0.239 ± 0.028	0.050 ± 0.005*
C22 :5 n-3	0.429 ± 0.017	0.063 ± 0.004*	0.308 ± 0.032	0.023 ± 0.002*
C22 :6 n-3	8.799 ± 0.355	3.662 ± 0.245*	6.167 ± 0.727	1.280 ± 0.071*
C18:2 cis-9,trans-11	0.035 ± 0.002	0.035 ± 0.002	0.048 ± 0.002	0.049 ± 0.001
C18:2 trans-10,cis-12	0.017 ± 0.001	0.017 ± 0.001	0.008 ± 0.001	0.003 ± 0.001*
C18:2 cis-9,cis-11	0.017 ± 0.002	0.026 ± 0.003*	0.029 ± 0.001	0.079 ± 0.004*
C18:2 trans-11,trans-13	0.015 ± 0.002	0.029 ± 0.002*	0.032 ± 0.006	0.107 ± 0.004*
C18:2 trans-9,trans-11	0.020 ± 0.003	0.036 ± 0.003*	0.005 ± 0.003	0.000 ± 0.000

Fatty acid profile (expressed as % of identified fatty acids) in mice fed a control (CT-1, n = 9; CT-3, n = 4) or an n-3 PUFA-depleted diet during one (DEF-1, n = 9) or three months (DEF-3, n = 7).

Data are the means ± SEM.

*p<0.05 versus CT mice (Student’s t-test).