Table 2. Frequency of B cell subsets in miR-181a/b het and ko mice.
| Adult | Neonatal | |||
|---|---|---|---|---|
| Subset | het | ko | het | ko |
| Splenocytes (absolute counts) | 8.9 x 107 ± 5.0 x 107 | 1.1 x 108 ± 5.0 x 107 | 5.1 x 106 ± 4.3 x 106 | 3.6 x 106 ± 1.9 x 106 |
| • B cells | 40.2 ± 2.3 | 37.6 ± 5.2 | 21.9 ± 7.6 | 24.6 ± 15.5 |
| – T1 | 24.8 ± 11.7 | 28.1 ± 9.6 | 96.2 ± 2.5 | 96.6 ± 0.8 |
| – T2 | 2.4 ± 1.3 | 3.0 ± 1.5 | 0.8 ± 0.6 | 0.7 ± 0.6 |
| – MZp/MZ | 12.1 ± 3.0 | 14.3 ± 4.5 | 0.6 ± 0.8 | 0.1 ± 0.1 |
| – MZp | 23.7 ± 3.7 | 22.0 ± 5.6 | 1.5 ± 2.5 | 2.6 ± 3.2 |
| – MZ | 75.5 ± 4.0 | 77.1 ± 6.0 | 64.5 ± 55.9 | 53.8 ± 55.3 |
| – FM | 58.1 ± 11.5 | 51.1 ± 9.0 | 0.3 ± 0.3 | 0.5 ± 0.2 |
FM: follicular mature; MZ: marginal zone; MZp: marginal zone precursor; T1 & T2: transitional 1 & 2
Adult: het/ko n = 11 each; Neonatal: het/ko n18/14 (pooled)
The frequency of total B cells (as percentage of total spleen cells; splenocytes), T1 & T2, MZp/MZ, and FM cells (as percentage of total B cells) as well as MZ and MZp cells (as percentage of MZp/MZ cells) is shown.