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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Nature. 2017 May 17;545(7655):439–445. doi: 10.1038/nature22326

Figure 6. Deconvolution of vascular niche angiocrine signals in rEC-HSPC generation.

Figure 6

a, Quantification of Runx1-IRES-GFP Fgrs-ECs Cxcr4fl/fl or Cxcr4−/− and their derivatives during reprogramming. Data represent mean ± s.e.m. (n = 4); two-tailed unpaired t-test. b, Schematic representation of angiocrine pathways involved in conversion of adult endothelial cells into HSPCs.