TABLE 3.

Commonly coregulated lipid subclasses between plasma and tissues

Tissue	Saturation (Plasma vs. Tissue)		Acyl-Chain Length (Plasma vs. Tissue)
	Control	Diabetic	Control	Diabetic
Kidney	DAG low, LPE low, PA low, PA high, PC low	CE low, LPE low, PA low, PG low, SM high	LPC bottom, LPE mid, PA mid, PA top, PI top	LPE top, PA bottom, PI top, PlPE bottom, SM bottom, SM mid
Nerve	CL high, DAG low, LPE low, LPE high, PA high	CE low, LPC low, LPE low, PA low, PA high, PG low, PlPE high	CL mid, LPC bottom, LPC mid, LPE bottom, LPE mid, LPE top, PA mid, PA top, PE bottom, PG mid, SM bottom	LPC bottom, LPE bottom, LPE mid, LPE top, PA bottom, PA mid, PA top, PI top
Retina	CE high, PA high, PG low, PG high, PlPE low	CE low, LPE high, PA high, PG low	CE mid, LPE top, PA bottom, PA mid, PA top, PG bottom, PG mid, SM bottom, SM mid	LPC bottom, LPE bottom, LPE mid, LPE top, PA mid, PA top
Liver	CE low, CE high, DAG low, LPC low, LPE low, LPE high, PG low, PG high, PlPE low, SM low	CE low, LPE low, PA low, PA high, PG low	CE mid, DAG bottom, DAG top, LPC bottom, LPE bottom, LPE mid, LPE top, PA mid, PA top, PG bottom, PG mid, PI top, PlPE bottom	LPC bottom, PA top, PI top

Commonly coregulated lipid subclasses between plasma and each tissue in 24-week-old db/+ and db/db mice. For saturation, each class was separated into low (unsaturated/monounsaturated) and high (polyunsaturated). For acyl-chain length, each class was divided into thirds (bottom, mid, top). P < 0.1 using correlation analysis at the set level, n = 10 per group. PlPE, plasmenyl-phosphatidylethanolamine. Data are also presented in supplemental Tables S7 and S8.