TABLE 2.
VLDL and LDL compositions of mouse plasma lipoproteins separated by FPLC
| TG | CE | FC | PL | Protein | |
| VLDL composition (%) | |||||
| Ldlr−/− | 90 ± 0.51 | 1.91 ± 0.10 | 0.44 ± 0.19 | 2.18 ± 0.16 | 5.68 ± 0.20 |
| LTp | 92 ± 0.12 | 1.81 ± 0.04 | 0.61 ± 0.12 | 1.39 ± 0.06 | 4.24 ± 0.12 |
| LDb | 88 ± 1.39 | 2.84 ± 0.36 | 1.34 ± 0.29 | 2.86 ± 0.28 | 7.86 ± 0.55 |
| LDL composition (%) | |||||
| Ldlr−/− | 10 ± 2 | 23 ± 0.9 | 17 ± 0.9 | 13 ± 0.6 | 37 ± 1.0 |
| LTp | 13 ± 1.5 | 22 ± 1.5 | 21 ± 2.0 | 12 ± 0.9 | 33 ± 1.2 |
| LDb | 12 ± 3.8 | 27 ± 0.9 | 7 ± 1.0 | 16 ± 0.6 | 37 ± 0.7 |
| P for LDL | |||||
| Ldlr−/− versus LTp | ns | ns | ns | ns | — |
| Ldlr−/− versus LDb | ns | 0.0201 | 0.0045 | 0.0213 | — |
| LTp versus LDb | ns | 0.0302 | 0.0246 | 0.0261 | — |
| P for VLDL | |||||
| Ldlr−/− versus LTp | ns | ns | ns | 0.0445 | 0.0087 |
| Ldlr−/− versus LDb | ns | ns | ns | ns | ns |
| LTp versus LDb | ns | ns | ns | 0.0358 | 0.0234 |
The VLDL and LDL compositions of Ldlr−/−, LTp, and LDb mice are expressed in percentage of total weight (percent of each lipid ± percent of SEM). Ps are tabulated. Statistical analyses were performed using two-tailed unpaired t-tests with Welch’s correction (GraphPad Prism software, version 5). P < 0.05 (two-tailed) was considered to be statistically significant. ns, not significant.