Fig. 2.

Whole-body insulin-mediated glucose utilization and hepatic glucose production in chow-fed DGKα KO and WT mice (group a). Whole-body glucose utilization was assessed in conscious DGKα KO (closed bar) and WT (open bar) mice. A: Basal and insulin-stimulated whole-body glucose utilization. B: Suppression of hepatic glucose production (HGP). C: Glucose infusion rate during the euglycemic-hyperinsulinemic clamp. D: Plasma insulin concentration during basal and insulin-stimulated conditions of the euglycemic-hyperinsulinemic clamp. Results are mean ± SEM (n = 7–10 mice).