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Hepatic Them1 expression promotes fatty acid oxidation in livers of chow-fed mice. Chow-fed mice were sacrificed at age 18 weeks. Analyses included ACSL activity (n = 3–6 per group) (A), relative mRNA expression of Acsl isoforms (n = 4 per group) (B), rates of fatty-acid oxidation (n = 3–5 per group) (C), plasma concentrations of β-hydroxybutryate (n = 6 per group) (D), and relative mRNA expression of Pparα and its target genes (n = 4 per group) (E). * P < 0.05.
