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. 2018 Feb 2;38(1):BSR20170656. doi: 10.1042/BSR20170656

Table 9. Multivariate survival analysis of OS using Cox’s regression model for breast cancer patients.

Genotypes B S.E.M. OR 95% CI P
EZH2 rs12670401 1.004 0.277 2.729 1.586–4.695 <0.001
EZH2 rs6464926 0.928 0.275 2.529 1.474–4.339 0.001
SMYD3VNTR 0.358 0.184 1.431 0.998–2.051 0.052
EZH2 mRNA 0.463 0.219 1.589 1.034–2.440 0.035
SMYD3mRNA 0.614 0.198 1.848 1.253–2.726 0.002
EZH2 protein 0.574 0.198 1.776 1.205–2.617 0.004
SMYD3 protein 0.495 0.191 1.640 1.128–2.385 0.010
Age −0.172 0.528 0.842 0.299–2.372 0.745
Age of menarche 0.158 0.205 1.171 0.783–1.750 0.443
Menopausal status 0.594 0.471 1.810 0.720–4.553 0.207
Tumor size 0.012 0.142 1.012 0.767–1.336 0.931
ER (+) −0.247 0.766 0.781 0.174–3.504 0.747
PR (+) 0.319 0.832 1.376 0.269–7.034 0.701
Histology −0.049 0.151 0.952 0.708–1.281 0.746
Clinical staging 1.193 0.237 3.298 2.072–5.249 <0.001
Lymph node metastasis 0.742 0.223 2.101 1.358–3.251 0.001
HER2 status 1.204 0.255 3.335 2.024–5.494 <0.001
FDRs with breast cancer −0.125 0.190 0.883 0.608–1.282 0.513
Subtypes of breast cancer −0.088 0.287 0.915 0.522–1.606 0.758
Metastasis situation 0.668 0.189 1.950 1.345–2.826 <0.001

Abbreviation: B, regression coefficient.