. Author manuscript; available in PMC: 2019 Feb 1.

Published in final edited form as: Mol Genet Genomics. 2017 Sep 11;293(1):119–128. doi: 10.1007/s00438-017-1365-6

Table 2.

Analysis of association of TFPI SNP rs10931292 with coagulation parameters.

Coagulation Indicator	Sample Size (AA/AG/GG)	P_adj			Effect [B (95% CI)]

		Additive	Dominant	Recessive	Additive	Dominant	Recessive
Fibrinogen	980/790/305	^a0.026	0.131	0.017	0.53 (0.06–1.00)	0.51 (−0.15–1.17)	1.14 (0.21–2.08)
Fibrinogen	980/790/305	^b0.027	0.136	0.018	0.52 (0.06–0.98)	0.51 (−0.16–1.17)	1.13 (0.20–2.07)
Prothrombin time	1,084/886/335	0.289	0.492	0.239	−0.19 (−0.55–0.17)	−0.18 (−0.69–0.33)	−0.44 (−1.17–0.29)
Prothrombin time	1,084/886/335	0.283	0.487	0.232	−0.20 (−0.56–0.16)	−0.18 (−0.69–0.33)	−0.45 (−1.17–0.29)
Activated partial thromboplastin time	1,079/866/330	0.308	0.274	0.606	−2.16 (−6.32–2.00)	−3.32 (−9.27–2.63)	−2.23 (−10.68–6.23)
Activated partial thromboplastin time	1,079/866/330	0.353	0.300	0.679	−1.97 (−6.13–2.19)	−3.15 (−9.10–2.80)	−1.78 (−10.24–6.68)
Thrombin time	992/786/296	0.595	0.915	0.216	0.14 (−0.38–0.67)	−0.04 (−0.79–0.71)	0.67 (−0.40–1.74)
Thrombin time	992/786/296	0.595	0.915	0.216	0.14 (−0.38–0.67)	−0.04 (−0.79–0.71)	0.68 (−0.40–1.75)

P_adj, P value obtained from multiple linear modeling after adjustment for age and gender^a or for age, gender and CAD^b.

Additive model = GG/AG/AA; Dominant model = GG+AG/AA; Recessive model = GG/AG+AA.