. Author manuscript; available in PMC: 2019 Feb 1.

Published in final edited form as: Mol Genet Genomics. 2017 Sep 11;293(1):119–128. doi: 10.1007/s00438-017-1365-6

Table 4.

Analysis of allelic association between TFPI SNP rs10931292 and CAD.

Population (n, case/control)	P_hwe	Risk Allele	Frequency (Case/Control)	Before adjustment		After adjustment

				P_obs^a	OR(95%CI)	P_adj^b	OR(95%CI)
Overall CAD (4,479/3,628)	0.08	G	0.34/0.33	0.08	1.06 (0.99–1.14)	0.08	1.07 (0.99–1.15)
Early-onset CAD (1,541/3,628)	0.08	G	0.33/0.33	0.94	1.00 (0.89–1.14)	0.64	1.04 (0.89–1.20)
Female CAD (1,698/1,329)	0.33	G	0.35/0.33	0.51	1.04 (0.93–1.16)	0.62	1.03 (0.91–1.16)
Male CAD (2,707/2,242)	0.20	G	0.33/0.32	0.05	1.09 (1.00–1.19)	0.07	1.09 (0.99–1.19)

P_hwe, P value from Hardy-Weinberg disequilibrium tests; P_obs, observed P value; P_adj, P value after adjustment for covariates of age and gender; OR, odds ratio; 95% CI, 95% confidence interval; Early-onset CAD, males age 50 years or younger; females age 55 years or younger at the first diagnosis of the disease.