Skip to main content
. Author manuscript; available in PMC: 2018 Sep 21.
Published in final edited form as: Mol Psychiatry. 2017 Aug 1;23(7):1614–1625. doi: 10.1038/mp.2017.159

Figure 5. Mice raised under EE are resistant to stress-induced spine loss and texture discrimination defects.

Figure 5

a, Schematic of EE. b, EE prevented RS-induced decrease in PV+ IN activity. c, Both stressed and unstressed EE mice had elevated activation of NG+ neurons compared to unstressed, non-EE control mice. d, Stress increased SOM+ neuron activation in both control and EE mice; EE had no effect on SOM+ neuron activation. e,f, EE increased both spine formation (e) and elimination (f) compared to unstressed, non-EE control mice. Stress did not further alter spine dynamics in EE mice. g, Both stressed and unstressed EE mice exhibited normal texture discrimination.