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. 2018 Jan 27;15(1):5–22. doi: 10.1007/s13311-017-0600-5

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Modulators of the hypothalamus–pituitary–adrenal (HPA) axis. There are multiple activators (→) and inhibitors (˧) of the HPA axis

GR = glucocorticoid receptor; PFC = prefrontal cortex; GABA = γ-aminobutyric acid; GLP-1 = glucagon-like peptide 1; NE = norepinephrine; 5-HT = 5-hydroxytryptamine