Table 1.
Sociodemographic and clinical characteristics of HIV-infected adults tested for hepatitis B surface antigen at antiretroviral therapy initiation in Zambia
| HBsAg-seropositive (n=66) | HBsAg-seronegative (n=346) | P value | |
|---|---|---|---|
|
| |||
| Age, in years | |||
| 18–29 | 19 (28.8) | 80 (23.1) | 0.45 |
| 30–39 | 31 (47.0) | 159 (46.0) | |
| 40+ | 16 (24.2) | 107 (30.9) | |
|
| |||
| Sex | |||
| Male | 34 (51.5) | 167 (48.3) | 0.63 |
| Female | 32 (48.5) | 179 (51.7) | |
|
| |||
| WHO clinical stage | |||
| 1 or 2 | 40 (61.5) | 198 (57.4) | 0.32 |
| 3 or 4 | 25 (38.5) | 147 (42.6) | |
|
| |||
| Tuberculosis | 9 (13.6) | 51 (14.7) | 0.83 |
|
| |||
| Alcohol consumption* | |||
| None/Moderate | 33 (50.0) | 211 (61.0) | 0.10 |
| Hazardous | 33 (50.0) | 135 (39.0) | |
|
| |||
| Median ALT, in U/L | 21 (14–37) | 19 (14–28) | 0.20 |
|
| |||
| Median CD4+ count, in cells/mm3 | 237 (129–347) | 204 (112–324) | 0.30 |
|
| |||
| LSM, in kiloPascals | 5.8 (4.4–6.4) | 4.9 (4.4–5.8) | 0.01 |
All values are median (IQR) or number (%). Abbreviations: WHO, World Health Organization; ALT, alanine transaminase; LSM, liver stiffness measurement; CD4, cluser of differentiation 4.
*
Hazardous drinking was defined as AUDIT-C score of >2 for women and >3 for men.