Upregulation of Rac family proteins in colitis tissues. A-C. Rac1, Rac2 and Rac3 expression in normal colon tissues and the flamed colonic tissues from UC patients were collected from GEO database (GDS3268) and analyzed. (n=70 for normal group; n=63 for UC group). D. Real-time PCR was performed to detect Rac1, Rac2 and Rac3 expression in the colonic tissue of mice with or without 2% DSS treatment. The relative expression of Rac1, Rac2 and Rac3 was analyzed. (n=4, *, P<0.05; **, P<0.01).