Inhibition of Rac prevents inflammation during CAC formation. A. Immunofluorescent staining analysis of iNOS and Ly6G expression in colonic tissue of CAC mice. Scale bar = 100 μm. B. The number of iNOS and Ly6G positive cells were counted and analyzed. n=4, **, P<0.01. C. Immunofluorescent staining analysis of iNOS and F4/80 expression in colonic tissue of CAC mice. Scale bar = 100 μm. D. The number of iNOS and F4/80 positive cells were counted and analyzed. n=4, **, P<0.01. E-H. ELISA analysis of IL-6, TNF-α, INF-γ and IL-1β expression in colonic tissue of CAC mice. n=3, **, P<0.01.